1. Pirates of the Caribbean: At World’s End

Buena Vista

Weekend Gross: $43,188,000

Total Gross: $216,527,000

2. Knocked Up

Universal

Weekend Gross: $29,284,000

Total Gross: $29,284,000

3. Shrek the Third

Dreamworks SKG

Weekend Gross: $26,704,000

Total Gross: $254,611,000

4. Mr. Brooks

MGM

Weekend Gross: $10,020,000

Total Gross: $10,020,000

5. Spider-Man 3

Sony Pictures

Weekend Gross: $7,500,000

Total Gross: $318,264,000

Totals courtesy of www.the-numbers.com.