1. Pirates of the Caribbean: At World’s End
Buena Vista
Weekend Gross: $114,732,820
Total Gross: $127,972,864

2. Shrek the Third
Dreamworks SKG
Weekend Gross:  $53,039,992
Total Gross: $203,378,450

3. Spider-Man 3
Sony Pictures
Weekend Gross: $14,335,436
Total Gross: $303,977,758

4. Bug
Lionsgate
Weekend Gross: $3,245,556
Total Gross: $3,245,556

5. Waitress
Fox Searchlight
Weekend Gross: $3,076,035
Total Gross: $5,593,423

Totals courtesy of www.the-numbers.com.